diff --git a/docs/release-notes/.FSharp.Compiler.Service/11.0.100.md b/docs/release-notes/.FSharp.Compiler.Service/11.0.100.md
index 785eccfd126..678324382d0 100644
--- a/docs/release-notes/.FSharp.Compiler.Service/11.0.100.md
+++ b/docs/release-notes/.FSharp.Compiler.Service/11.0.100.md
@@ -1,5 +1,6 @@
 ### Fixed
 
+* Fix FS3236 when taking the address of an untyped generalized `let` binding (e.g. `let ffff = ValueNone`) passed to an `inref` parameter. ([Issue #19608](https://github.com/dotnet/fsharp/issues/19608), [PR #19948](https://github.com/dotnet/fsharp/pull/19948))
 * Fix IntelliSense not suggesting later named arguments after the first one is autocompleted, for methods (including overloaded methods like `Task.Factory.StartNew`). ([Issue #19906](https://github.com/dotnet/fsharp/issues/19906), [PR #19940](https://github.com/dotnet/fsharp/pull/19940))
 * Restore packaging of an F# design-time type provider that is activated via a `ProjectReference` carrying `IsFSharpDesignTimeProvider="true"`. The provider assembly is again included under `fsharp41` when packing (including `pack --no-build`); `PackageFSharpDesignTimeTools` now resolves the provider via `GetTargetPath`, which works in `dotnet pack`'s `BuildProjectReferences=false` content build without forcing an early `ResolveReferences`. ([Issue #18924](https://github.com/dotnet/fsharp/issues/18924), [PR #19979](https://github.com/dotnet/fsharp/pull/19979))
 * Provided types used from multiple files no longer produce spurious FS0001 type mismatches under parallel compilation; provided-type entities are now interned so every file linking a given provided type shares one entity. ([PR #19969](https://github.com/dotnet/fsharp/pull/19969))
diff --git a/src/Compiler/TypedTree/TypedTreeOps.ExprOps.fs b/src/Compiler/TypedTree/TypedTreeOps.ExprOps.fs
index bdebaf40ff5..91ed02ee1a3 100644
--- a/src/Compiler/TypedTree/TypedTreeOps.ExprOps.fs
+++ b/src/Compiler/TypedTree/TypedTreeOps.ExprOps.fs
@@ -192,8 +192,10 @@ module internal AddressOps =
                 None, exprForValRef m vref, readonly, writeonly
 
             // LVALUE of "x" where "x" is mutable local, mutable intra-assembly module/static binding, or operation doesn't mutate.
-            // Note: we can always take the address of mutable intra-assembly values
-            | Expr.Val(vref, _, m) when MustTakeAddressOfVal g vref || CanTakeAddressOfImmutableVal g m vref mut ->
+            // Note: we can always take the address of mutable intra-assembly values.
+            // The second pattern matches a type-instantiated local value reference produced by TcVal for generalized let bindings.
+            | Expr.Val(vref, _, m)
+            | Expr.App(Expr.Val(vref, _, _), _, _, [], m) when MustTakeAddressOfVal g vref || CanTakeAddressOfImmutableVal g m vref mut ->
                 let readonly = not (MustTakeAddressOfVal g vref)
                 let writeonly = false
                 checkTakeNativeAddress readonly
diff --git a/tests/FSharp.Compiler.ComponentTests/Conformance/Expressions/DataExpressions/AddressOf/AddressOf.fs b/tests/FSharp.Compiler.ComponentTests/Conformance/Expressions/DataExpressions/AddressOf/AddressOf.fs
index 4005d80bf5d..b19f397fc57 100644
--- a/tests/FSharp.Compiler.ComponentTests/Conformance/Expressions/DataExpressions/AddressOf/AddressOf.fs
+++ b/tests/FSharp.Compiler.ComponentTests/Conformance/Expressions/DataExpressions/AddressOf/AddressOf.fs
@@ -131,19 +131,32 @@ let test () =
         |> shouldSucceed
 
     [<Fact>]
-    let ``Issue 18841 - plain let discard with no address-of still compiles`` () =
+    let ``Issue 19608 - address of untyped ValueNone compiles`` () =
         Fsx """
 module Test
 
-type S =
-    struct
-        val Field: int
-    end
+let x (y: inref<ValueOption<int>>) = ()
 
 let test () =
-    let s = S()
-    let _ = s
+    let ffff = ValueNone
+    x &ffff
+        """
+        |> asLibrary
+        |> compile
+        |> shouldSucceed
+
+    [<Fact>]
+    let ``Issue 19608 - native address of untyped ValueNone binding fails`` () =
+        Fsx """
+#nowarn "51"
+
+module Test
+
+let test () =
+    let ffff = ValueNone
+    let _ = &&ffff
     ()
         """
         |> typecheck
-        |> shouldSucceed
+        |> shouldFail
+        |> withErrorCode 256